Enhanced Skin Permeability of Ascorbic Acid after CLEAR + BRILLIANT Perméa Laser Treatment
نویسندگان
چکیده
Photoaging results in numerous clinical effects in the skin, including wrinkles, textural changes, dyspigmentation, telengiectasia, and lentigines. Long-term sunlight exposure has been shown to increase the risk of actinic keratoses and nonmelanoma skin cancer. Amongst the approaches undertaken to reduce this risk are laser skin resurfacing as well as topical therapies. Concerning the latter, ascorbic acid, commonly known as vitamin C, has received much attention for its ability to reduce ultraviolet (UV)-induced photodamage. The mechanism underlying this photoprotective effect is thought to be related to ascorbic acid’s antioxidant activity. When human subjects topically applied L-ascorbic acid as a 10% solution for 5 days prior to UVB irradiation, a significant reduction in erythema was observed when compared to vehicle controls.
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